• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

The effect of herpes zoster vaccination on the occurrence of deaths due to dementia in England and Wales
CONCLUSIONS: Our findings indicate that HZ vaccination improved cognitive function at a fairly advanced stage of the dementia disease process because most individuals whose underlying cause of death was dementia during our nine-year follow-up period were likely already living with dementia at the start of the HZ vaccination program. By using a different population, type of data, and outcome than our prior study in Welsh electronic health record data, this analysis adds to the evidence base that HZ vaccination slows, or potentially even prevents, the natural history of dementia.PMID:37732219 | PMC:PMC10508823 | DOI:10.1101/2023.09.08.23295225
Source: Herpes - September 21, 2023 Category: Infectious Diseases Authors: Felix Michalik Min Xie Markus Eyting Simon He ß Seunghun Chung Pascal Geldsetzer Source Type: research

Causal evidence that herpes zoster vaccination prevents a proportion of dementia cases
medRxiv. 2023 May 25:2023.05.23.23290253. doi: 10.1101/2023.05.23.23290253. Preprint.ABSTRACTThe root causes of dementia are still largely unclear, and the medical community lacks highly effective preventive and therapeutic pharmaceutical agents for dementia despite large investments into their development. There is growing interest in the question if infectious agents play a role in the development of dementia, with herpesviruses attracting particular attention. To provide causal as opposed to merely correlational evidence on this question, we take advantage of the fact that in Wales eligibility for the herpes zoster vacc...
Source: Herpes - June 9, 2023 Category: Infectious Diseases Authors: Markus Eyting Min Xie Simon He ß Simon He ß Pascal Geldsetzer Source Type: research

Vaccine-preventable hospitalisations in adult mental health service users: a population study
CONCLUSIONS: MH service users have increased risk of hospitalisation for many vaccine-preventable conditions. This may be due to reduced vaccination rates, more severe illness requiring hospitalisation, greater exposure to infectious conditions or other factors. People living with mental illness should be prioritised in vaccination strategies.PMID:37016779 | DOI:10.1017/S0033291723000776
Source: Psychological Medicine - April 5, 2023 Category: Psychiatry Authors: Grant Sara Patrick Gould Jackie Curtis Wendy Chen Michael Lau Parashar Ramanuj David Currow Philip Burgess Source Type: research

Associations between severe and notifiable respiratory infections during the first trimester of pregnancy and congenital anomalies at birth: a register-based cohort study
CONCLUSION: This large population-based study found severe acute respiratory infection in first trimester of pregnancy was associated with a higher risk of selected major cardiovascular anomalies in babies. These findings support measures to prevent acute respiratory infections in pregnant women including through vaccination.PMID:36964492 | PMC:PMC10037767 | DOI:10.1186/s12884-023-05514-8
Source: Herpes - March 25, 2023 Category: Infectious Diseases Authors: Abrar A Chughtai Wen-Qiang He Bette Liu Source Type: research

Modeling the Impact of Exogenous Boosting and Universal Varicella Vaccination on the Clinical and Economic Burden of Varicella and Herpes Zoster in a Dynamic Population for England and Wales
Vaccines (Basel). 2022 Aug 28;10(9):1416. doi: 10.3390/vaccines10091416.ABSTRACTUniversal varicella vaccination (UVV) in England and Wales has been hindered by its potential impact on exogenous boosting and increase in herpes zoster (HZ) incidence. We projected the impact of ten UVV strategies in England and Wales on the incidence of varicella and HZ and evaluated their cost-effectiveness over 50 years. The Maternal-Susceptible-Exposed-Infected-Recovered-Vaccinated transmission model was extended in a dynamically changing, age-structured population. Our model estimated that one- or two-dose UVV strategies significantly red...
Source: Herpes - September 23, 2022 Category: Infectious Diseases Authors: Oluwaseun Sharomi Ilaria Xausa Robert Nachbar Matthew Pillsbury Ian Matthews Tanaz Petigara Elamin Elbasha Manjiri Pawaskar Source Type: research

Reduced dementia incidence after varicella zoster vaccination in Wales 2013-2020
DISCUSSION: Our study shows a clear association of shingles vaccination with reduced dementia, consistent with other observational cohort studies. The association may reflect selection bias with people choosing to be vaccinated having a higher healthy life expectancy.PMID:35434253 | PMC:PMC9006884 | DOI:10.1002/trc2.12293
Source: Herpes - April 18, 2022 Category: Infectious Diseases Authors: Christian Schnier Janet Janbek Richard Lathe J ürgen Haas Source Type: research